Effects of loss-of-function of AtMIKC* MADS-box genes on the mature Arabidopsis pollen transcriptome.
MADS-complexes regulate transcriptome dynamics during pollen maturation.
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Age, Specimen part
View SamplesTo provide novel insights into the molecular basis of floral initiation, RNASeq was used to characterize the soybean transcriptome of leaf and micro-dissected shoot apical meristem at different time points after short-day treatment.
No associated publication
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No sample metadata fields
View SamplesRNA sequencing data for four cell lines representing different stages during malignant transformation.
Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model.
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No sample metadata fields
View Samplesthe mRNA expression of pig lung tissue. there are four groups: LW pigs infected with PCV2, LW pigs control, Yorkshire × Landrace (YL) pigs infected with PCV2, Yorkshire × Landrace (YL) pigs control.
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Sex, Age, Specimen part, Disease, Disease stage, Cell line, Treatment
View SamplesVEGF and VEGFB Play Balancing Roles in Adipose Differentiation, Gene Expression and Function
No associated publication
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Sex, Specimen part, Cell line
View Samplesgene expression study on brain and lung under Dip2a regulation to better understand the role of Dip2a gene during mice brain and lung development.
Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9.
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Sex, Specimen part, Cell line
View SamplesSoybean transcript fluctuations were observed in response to Rhizoctonia solani AG-1 IA causing Rhizoctonia foliar blight. The overall goal was to observe the general transcriptome fluctuations using RNAseq Illumina HiSeq analysis.
No associated publication
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Specimen part, Disease
View SamplesSmall RNA seq following over expression of miR-218 in HepG2 cells; mRNA expression following perturbation of miR-218 in primary mouse motor neurons
No associated publication
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Sex, Specimen part
View SamplesProgranulin mutations found in frontotemporal lobar degeneration (FTLD) cases typically result in heterozygous loss-of-function. To assess the impact of PGRN deficiency on gene expression, particularly of genes associated with lipid metabolism, in the brain, we sequenced the total RNA extracted from whole brains from 7-month-old female Grn+/+, Grn+/–, and Grn–/– mice and determined the differential expression of transcripts in PRGN-deficient (Grn+/- and Grn-/-) and wild type (Grn+/+) brains.
No associated publication
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Sex, Age, Specimen part, Cell line
View SamplesCuticular wax is a major composition of plant surface cuticle, which exerts crucial functions in optimizing plant growth. Histone acetylation regulates gene expression of diverse biological processes, but little is known about its role in cuticular wax synthesis. Here we observed that mutation of Arabidopsis histone acetyltransferase GCN5 gene impaired stem cuticular wax accumulation. Furthermore, three target genes of GCN5 (CER3, CER26 and CER1-L1) were identified by RNA-Seq and ChIP assays. Consistently, H3K9/14 acetylation levels in promoter regions of CER3, CER26 and CER1-L1 were significantly decreased in gcn5 as compared to wild type. Notably, overexpression of CER3 in the gcn5 mutant restored the stem cuticular wax accumulation. Collectively, these data demonstrate that Arabidopsis GCN5 is involved in stem cuticular wax accumulation by modulating CER3 expression via H3K9/14 acetylation, which present evidence that histone acetylation plays an important role in cuticular wax biosynthesis
No associated publication
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Specimen part
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