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accession-icon GSE109501
Expression data of different regions of E11.5 mouse optic cups
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Optic fissue is a transient opening on the ventral side of developing optic cup. Failure in optic fissue closure will cause coloboma formation. The aim of this study was to compare optic fissue transcriptome with center optic cup to find optic fissue specific genes.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-109501

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE68243
Expression data from rat lung-resident mesenchymal stem cells and bone marrow-derived mesenchymal stem cells
  • organism-icon Rattus norvegicus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.0 ST Array (ragene10st)

Description

Rat lung-resident mesenchymal stem cells (LR-MSCs) were isolated via bronchoalveolar lavage from fibroblast growth factor-10 (FGF-10) pretreated lungs. We characterized the similarity and diversity between LR-MSCs and bone marrow-derived mesenchymal stem cells (BM-MSCs) by transcriptional profiling of these two types of cells.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-68243

Sample Metadata Fields

Specimen part

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accession-icon GSE108853
Screen of differential expressed genes from residual MHCC97H treated by POSTN or not
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Incomplete thermal ablation may induce invasiveness of hepatocellur carcinoma, however, the mechasim is not fully understood. Here, we investigated whether activated hepatic stellate cells would accelerate the progression of residual HCC after sublethal heat treatment via the secretion of POSTN.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-108853

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE112349
Expression data from heat-damaged MHCC97H treated by HGF
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Incomplete heat-damaged MHCC97H ususlly recurred. The mechanism of how residual HCC cells survive sublethal heat stress and develop rapid outgrowth remains poorly understood.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-112349

Sample Metadata Fields

Treatment

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accession-icon GSE51401
Expression data from tumor-associated endothelial cells of hepatocellular carcinoma
  • organism-icon Homo sapiens
  • sample-icon 54 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Primary uncultured CD31+ and CD105+ tumor endothelial cells (TEC), non-tumor endothelial cells (NEC) ,remnant cells from tumor (TC) and non-tumor liver tissue (NTC)of HCC tissues from patientswere isolated by magnetic-activated cell sorting. Affymetrix Human Gene ST Arrays were used to determine gene expression profiles of HCC cells and matched TEC and NEC cells.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-51401

Sample Metadata Fields

Specimen part

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accession-icon GSE16974
Retinal gene expression in Egr-1 knock-out mice during development (p30 and p42)
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

In chicks, the avian homologue of the early growth response protein-1 (ZENK) has been shown to be increased in a special cell type of the retina, the glucagonergic amacrine cells, under conditions that lead to a reduction in eye growth (myopic defocus, recovery of myopia) and decreased under conditions that enhance ocular growth (hyperopic defocus, form-deprivation). The investigation of Egr-1 knock-out mice showed that homozygous knock-out mice with no functional Egr-1 protein developed relative axial myopia at the age of 42 and 56 days, compared to heterozygous- and wildtype Egr-1 knock-out mice.

Publication Title

Microarray analysis of retinal gene expression in Egr-1 knockout mice.

Alternate Accession IDs

E-GEOD-16974

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon GSE11439
Retinal gene expression in chicks during imposed myopic defocus
  • organism-icon Gallus gallus
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

Description

The retina plays an important regulatory role in ocular growth. To screen for new retinal candidate genes that could be involved in the inhibition of ocular growth, we used chick microarrays to analyze the changes in retinal mRNA expression after myopic defocus was imposed by positive lens-wear.

Publication Title

Microarray analysis of retinal gene expression in chicks during imposed myopic defocus.

Alternate Accession IDs

E-GEOD-11439

Sample Metadata Fields

Sex, Age

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accession-icon SRP167336
Transcriptome analysis of tumors that develop in mice following injection of AGS cell lines
  • organism-icon Homo sapiens
  • sample-icon 33 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

RNA-seq study of tumors that develop in mice after injection of gastric carcinoma cell line, AGS, with or without Epstein-Barr virus infection

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line

View Samples
accession-icon GSE31774
Effect of loss of function of Gal11/Med15 and Med3 from the Mediator tail module in budding yeast
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

Gene expression was compared for wild type yeast (BY4741) and yeast lacking Gal11/Med15 and Med3, or from a gal11-myc med3 strain. The gal11-myc allele shows a partial loss of function when combined with med3. Expression was analyzed for yeast grown in YPD as well as in CSM.

Publication Title

Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast.

Alternate Accession IDs

E-GEOD-31774

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE1639
Rpd3 and histone H3 and H4 deletions/mutations
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome S98 Array (ygs98)

Description

Signal intensity data for rpd3 delete, H3delta(1-28), H3(K4,9,14,18,23,27Q), H4delta(2-26), H4(K5,8,12,16Q), rpd3 delete H3delta(1-28), and rpd3 delete H4(K5,8,12,16Q) yeast grown in rich (YPD) media

Publication Title

Genome-wide analysis of the relationship between transcriptional regulation by Rpd3p and the histone H3 and H4 amino termini in budding yeast.

Alternate Accession IDs

E-GEOD-1639

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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