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accession-icon GSE64576
Gene expression data of OsGRAS23 overexpression transgenic rice plants under normal and drought stress conditions
  • organism-icon Oryza sativa
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

GRAS transcription factors are plant-specific proteins that play diverse roles in plant development and abiotic stress responses, over-expression of OsGRAS23, a GRAS gene in rice, showed improved drought resistance.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-64576

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-2536
Transcription profiling of a Bur1 ts mutant, a Rfa1 ts mutant and of a Bur1-Rfa1 double mutant yeast strain
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

Transcription profiling of a Bur1 ts mutant (bur1-7), a Rfa1 ts mutant (rfa1-249) and of a Bur1-Rfa1 double mutant (bur1-7 rfa1-249) yeast strain.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon E-MEXP-2581
Transcription profiling of yeast with SCP160 gene expression shut down using doxycycline
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The influence of the shut-down of SCP160 gene expression on the yeast transcriptome was investigated in the present study.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Compound

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accession-icon E-MEXP-3126
Iwr1 directs RNA polymerase II nuclear import
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

Effect of the deletion of IWR1 (YDL115c) on the Saccharomyces cerevisiae transcriptome

Publication Title

Iwr1 directs RNA polymerase II nuclear import

Alternate Accession IDs

None

Sample Metadata Fields

Sex

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accession-icon GSE65988
Expression profiling of DLBCL subtypes PDX model
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Identify the PDX model of DLBCL subtypes by the microarray expression profiling

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-65988

Sample Metadata Fields

Specimen part, Subject

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accession-icon GSE137976
Expression Data from Arabidopsis ULT1 and CLF Mutants
  • organism-icon Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

ULT1 and CLF function antagonistically as epigenetic regulators of gene expression in Arabidopsis. We sought to identity their global downstream target genes at two stages of plant development and determine their common targets.

Publication Title

The Trithorax Group Factor ULTRAPETALA1 Regulates Developmental as Well as Biotic and Abiotic Stress Response Genes in Arabidopsis.

Alternate Accession IDs

E-GEOD-137976

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon E-MEXP-88
RNAi knock down in Drosophila of THO2 and HPR1 proteins from S2 cells
  • organism-icon Drosophila melanogaster
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

THO2 and HPR1 proteins were co-depleted from Drosophila S2 cells and their role in mRNA export analysed by comparing total RNA and cytoplasmic RNA

Publication Title

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha.

Alternate Accession IDs

None

Sample Metadata Fields

Cell line

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accession-icon GSE28297
Expression data from WT (Columbia) and pifq (pif1pif3pif4pif5) mutant Arabidopsis seedlings
  • organism-icon Arabidopsis thaliana
  • sample-icon 29 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Plants respond to changes in the red:far red ratio (R:FR) of incident light. A reduction in this ratio (increase in FR) results in the Shade Avoidance Response (SAR) with associated changes in gene expression. The Phyotchrome-Interacting Factors (PIFs) are bHLH transcription factors known to be involved in the SAR. An analysis of changes in gene expression in WT and quadruple pif1pif3pif4pif5 (pifq; Leivar et al., 2008 (PMID 19920208)) mutant seedlings in response to an increase in FR should identify primary targets of PIF signaling.

Publication Title

Dynamic antagonism between phytochromes and PIF family basic helix-loop-helix factors induces selective reciprocal responses to light and shade in a rapidly responsive transcriptional network in Arabidopsis.

Alternate Accession IDs

E-GEOD-28297

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE17159
Gene expression in pif1pif3pif4pif5 mutant under dark or red light conditions
  • organism-icon Arabidopsis thaliana
  • sample-icon 29 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Light initiates the seedling deetiolation transition by promoting major changes in gene expression mainly regulated by phytochrome (phy) photoreceptors. During the initial dark-to-light transition, phy photoactivation induces rapid changes in gene expression that eventually lead to the photomorphogenic development. Recent reports indicate that this process is achieved by phy-induced degradation of Phy-Interacting bHLH transcription Factors (PIFs) PIF1, PIF3 PIF4 and PIF5, which are partly redundant constitutive repressors of photomorphogenesis that accumulate in darkness. In order to test whether light/phy-regulated gene expression occurs through these PIFs, we have performed whole-genome expression analysis in the pif1pif3pif4pif5 quadruple mutant (pifq).

Publication Title

Definition of early transcriptional circuitry involved in light-induced reversal of PIF-imposed repression of photomorphogenesis in young Arabidopsis seedlings.

Alternate Accession IDs

E-GEOD-17159

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE76250
Comprehensive transcriptome profiling reveals multigene signatures in triple negative breast cancer
  • organism-icon Homo sapiens
  • sample-icon 197 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

To develop and validate novel multigene signatures to facilitate individualized treatment of TNBC patients By integrating expression profiles of messenger RNAs (mRNAs) and long non-coding RNAs (lncRNAs).

Publication Title

Comprehensive Transcriptome Profiling Reveals Multigene Signatures in Triple-Negative Breast Cancer.

Alternate Accession IDs

E-GEOD-76250

Sample Metadata Fields

Sex, Specimen part, Disease stage

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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