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accession-icon E-MEXP-3120
Transcription profiling by array of arabidopsis wild type and met1 mutant calli cultured on shoot induction medium for 0, 4 and 6 hours
  • organism-icon Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Comparison of met1 mutant with control

Publication Title

DNA methylation and histone modifications regulate de novo shoot regeneration in Arabidopsis by modulating WUSCHEL expression and auxin signaling

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part, Time

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accession-icon E-MEXP-3292
Zhang-maize-MS-MP-UFO
  • organism-icon Zea mays
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Maize Genome Array (maize)

Description

Comparison of Zea mays mature silk (MS), mature pollen (MP) and unfertilized ovary (UFO).

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Age, Specimen part, Time

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accession-icon E-MEXP-3127
Transcription profiling by array of Arabidopsis embryonic calluses treated with synthetic auxin or N-1-naphthylphthalamic acid, an auxin polar transport inhibitor
  • organism-icon Arabidopsis thaliana
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

transcription profiling of different development stage and different treatment

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE18491
Expression data from maize endosperm
  • organism-icon Zea mays
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Maize Genome Array (maize)

Description

Despite much knowledge is well-known on the transcriptional and enzymological regulation of many genes in starch synthesis, including SBEb, Waxy, and SUS-SH1 genes, less information is available on their expression profiles as a consequence of their dysfunction. Hence, transcriptional adjustments in response to mutations were required for a better understanding of starch biosynthesis pathway, others metabolism and cell response.

Publication Title

Genome-wide transcriptional analysis of maize endosperm in response to ae wx double mutations.

Alternate Accession IDs

E-GEOD-18491

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-2350
Transcription profiling by array of young inflorescences of AP1∷AtIPT4 Arabidopsis thaliana transgenic plants to identify the candidate genes responsive to cytokinin
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The aim of this experiment is to identify the candidate genes responsive to cytokinin in Arabidopsis floral development. For this purpose, AtIPT4 gene under the control of the AP1 promoter was transformed into wild type plants of Arabidopsis. The transcriptional profiles of the young inflorescence of AP1::AtIPT4 transformants and wild-type plants are compared.

Publication Title

Cytokinin overproduction-caused alteration of flower development is partially mediated by CUC2 and CUC3 in Arabidopsis.

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part

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accession-icon GSE49306
Genome-wide gene expression profiles in lung tissues of pig breeds differing in resistance to porcine reproductive and respiratory syndrome virus
  • organism-icon Sus scrofa
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

Porcine reproductive and respiratory syndrome caused by porcine reproductive and respiratory syndrome virus (PRRSV) is an infectious disease characterized by severe reproductive deficiency in pregnant sows, respiratory symptoms in piglets, and high mortality. In this study, we employed Affymetrix microarray chip technology to compare the gene expression profiles of lung tissue samples from Dapulian (DPL) pigs (a Chinese indigenous pig breed) and DurocLandraceYorkshire (DLY) pigs after infection with PRRSV. During infection with PRRSV, the DLY pigs exhibited the range of clinical features that typify the disease, while the DPL pigs exhibited only mild signs of the disease. The percentage of CD8+ T cells in the DPL pigs was significantly higher than that in the DLY pigs at 21 days post-infection (dpi) (p< 0.05). Interleukin (IL) 1 beta (IL-1) and IL-2 levels showed significant differences between the DPL and DLY pigs at 0 and 7 dpi (p< 0.01). For IL-10, the DLY pigs had significantly higher values than the DPL pigs at 0 and 7 dpi (p< 0.01). Significant differences were apparent between the DPL and DLY pigs in terms of their tumor necrosis factor-alpha (TNF-) and interferon (IFN)-gamma (IFN-) levels at 0 and 7 dpi (p< 0.01). Microarray data revealed 16 differentially expressed genes in the lung tissue samples from the DLY and DPL pigs (q5%), of which LOC100516029 and LOC100523005 were up-regulated in the PRRSV-infected DPL pigs, while the other 14 genes were down-regulated in the PRRSV-infected DPL pigs compared with the PRRSV-infected DLY pigs. The expression levels of 10 of the 16 genes, namely CCDC84, C6ORF52, THYMOSIN, PRVE, HSPCB, CYP2J2, AMPD3, TOR1AIP2, PTGES3, and ACOX3, were validated by real-time quantitative RT-PCR. This study provides a platform for further investigation of the molecular mechanisms underlying the differential immune responses to PRRSV infection in different breeds or lines of pig.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-49306

Sample Metadata Fields

Specimen part

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accession-icon ERP001184
MS MP MO SL RNA-Seq
  • organism-icon Zea mays
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

RNA-sequencing of 7 tissues of maize inbred line Zheng 58: mature silk (MS), mature pollen (MP), mature ovary (MO), and 6-days old seedling (SL), immature silk (IMS), silk at 20min after pollination (20MAP), silk at 3h after pollination (3HAP)

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part

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accession-icon GSE73802
Identification of Drosophila Mid regulated genes in embryos
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Drosophila midline(mid), encodes a T-box transcription factor that is required for cell fate specification and tissue morphogenesis during a series of developmental processes. However, little is known about the target of Mid.

Publication Title

The T-box transcription factor Midline regulates wing development by repressing wingless and hedgehog in Drosophila.

Alternate Accession IDs

E-GEOD-73802

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE74592
Identification of Drosophila MBF1 regulated genes in embryos
  • organism-icon Drosophila melanogaster
  • sample-icon 1 Downloadable Sample
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Multiprotein bridging factor 1(MBF1), a transcriptional co-activator that can regulate transcription by forming a bridge between the TATA-box-binding protein and gene-specific transcription factors. MBF1 is required for organ development and environmental stress responses. However, the targets of MBF1 is unknown.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-74592

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE36917
Identication of Drosophila TDF/Apt regulated genes in embryos
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Drosophila tdf, another name apontic (apt), encodes a bZIP transcription factor that is required for the development of trachea, heart, head and neural system. However, little is known about the target of TDF/Apt.

Publication Title

Evolutionarily conserved transcription factor Apontic controls the G1/S progression by inducing cyclin E during eye development.

Alternate Accession IDs

E-GEOD-36917

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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