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Mus musculus
72 Downloadable Samples
Illumina HiScanSQ
Description
we construct a comprehensive mouse transcriptomic BodyMap across 17 tissues of six-weeks old C57BL/6JJcl mice using RNA-seq. We find different expression patterns between protein-coding and non-coding genes. Liver and adrenal gland expressed the least complex transcriptome, whereas testis and ovary harbor more complex transcriptome than other tissues. We report a comprehensive list of tissue-specific genes across 17 tissues. Our study provides a unique resource of mouse gene-expression profiles, which is helpful for further biomedical research.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
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SRP072270- Mus musculus
- 50 Downloadable Samples
- Illumina HiSeq 2000
Description
To investigate the random X chromosome inactivation in vivo, we used allelic-specific RNA sequencing of single cells in mouse model. The intercross was between two genetically distant strains, C57BL/6 and PWK/Ph.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Disease, Disease stage, Cell line
View Samples- Glycine max
- 35 Downloadable Samples
- Illumina HiSeq 2000
Description
To obtain a comprehensive understanding of transcriptomic reprogramming under salt stress, we performed whole genome RNA sequencing on salt-treatment soybean seedlings, on two tissues in a time-course experiment (0h, 1h, 2h, 4 h, 24h and 48h). This time series dataset enables us to identify important hubs and connection of gene expressions. We highlighted the analysis of phytohormone signaling pathways and their possible cross-talking. Gene expression regulation also controls adjustment of carbon and nitrogen metabolism. In general, the treated seedlings had turned off the photosynthetic mechanism and enhanced sugar catabolism to provide energy for survival. Primary nitrogen assimilation was shut down while re-distribution of nitrogen resources was activated. Genes for other protective mechanisms were also induced, including structural modification, ion-sequestering, and scavenging of reactive oxygen species.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part, Disease, Treatment
View Samples- Drosophila melanogaster
- 25 Downloadable Samples
- Illumina HiSeq 2500
Description
In order to study translational control by cis-regulatory elements in untranslated region of mRNA, ribosome profiling assays during different developmental stages of Drosophila melanogaster and in S2 cells cultured in normal and stressful conditions were performed.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Sus scrofa
- 6 Downloadable Samples
- Illumina Genome Analyzer
Description
Porcine meat production is determined by total myofiber number, while during embryonic stages, total myofiber number is determined by primary myofiber number. Thus, primary myofiber is a crucial determinant factor of porcine adult meat production. Understanding the molecular mechanisms of distinct primary myofiber formation time in pig breeds with different meat production will help to improve pig meat production by genetic methods and benefit the researches concerning muscle development. In this study RNA-seq to uncover the molecular mechanisms of distinct primary myofiber formation time in pig breeds with different meat production (Landrace and Wuzhishan) by using longissimus dorsi muscle (LDM) samples during 3 early embryonic stages (18,21,28 dpc).
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part
View Samples SRP120123- Arabidopsis thaliana
- 5 Downloadable Samples
- Illumina HiSeq 2500
Description
The goals of this study is to determine alternative splicing events in Arabidopsis thaliana.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part
View Samples- Arabidopsis thaliana
- 4 Downloadable Samples
- Illumina HiSeq 2000
Description
The CLAVATA1(CLV1)-related Leucine-rich repeat receptor-like kinase BAM3 was previously reported to function additively to BAM1/2 in other aspects of plant development. Here we reported the important role of BAM3 in anther development. We demonstrated that in the anther, bam3-2 single mutant exhibited delayed tapetal degradation and a more extensively covered surface through cell biological analyses. Further transcriptomic studies revealed that 813 genes significantly expressed at the RNA level in the bam3-2 mutant compared with wild-type, which were enriched in pollen exine formation, lipid metabolism, lipid transfer, and proteolysis. Moreover, an intersection analysis of significantly regulated genes in bam3-2, DN-CLE19 and ams revealed BAM3, CLE19 and AMS commonly affected the expression level of many genes, especially genes invovled in pollen development such as CYP703A2?LAP6?TKPR2?CYP703B1?MS2?WBC27?MEE48?QRT3?LAP5?DRL1 and MYB103. These results suggested that BAM3 is a crucial executor during tapetum degradation and pollen exine formation and probably takes part in the CLE19-AMS signaling pathway during anther development process.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part
View Samples SRP192957- Danio rerio
- 3 Downloadable Samples
- Illumina HiSeq 2000
Description
MiR-430 is considered an important regulator during embryonic development, but genetic loss-of-function study is still lacking. Here we demonstrated that genetic deletion of the miR-430 cluster resulted in developmental defects in cell movement, germ layer specification, axis patterning and organ progenitor formation in zebrafish. To identify miR-430 targets, we collected the WT, miR-430-/- and rescued embryos at shield stage and performed transcriptome sequencing.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Age, Specimen part, Disease, Cell line, Treatment
View Samples- Rattus norvegicus
- 1 Downloadable Sample
- Illumina HiSeq 4000
Description
RNA-seq for Rattus norvegicus''s tumour between wild and medication administration team
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Drosophila melanogaster
- 1 Downloadable Sample
- Illumina HiSeq 2000
Description
Transcriptome comparison of ovaries and testes in flies with 12 or 20 His-GUs and WT (w1118).
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples