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accession-icon SRP107867
MDA5 effect during HRV and RSV infection in respiratory epithelial cells.
  • organism-icon Homo sapiens
  • sample-icon 44 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

A549 cells that had been transfected 48 hours earlier with siRNA to MDA5 or non-specific negative control siRNA, were uninfected or infected for 6, 12, 24, and 48 hours with HRV-B14 or RSV. For each time point, infections were performed in triplicate. Total cellular RNA were isolated using RNeasy Mini Kit (Qiagen). Multiplexed RNA libraries were prepared using the Truseq RNA sample prep kit (Illumina). Libraries were sequenced on a HiSeq 2000 Sequencing System (Illumina) to produce 50 bp single end reads. Sequencing reads were aligned with ELAND to the human reference genome version hg19.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line, Treatment

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accession-icon SRP076532
Transcriptome analysis of human monocytes 6h after stimulation with pathogens/vitamins
  • organism-icon Homo sapiens
  • sample-icon 46 Downloadable Samples
  • Technology Badge IconIon Torrent Proton

Description

Human monocytes were infected with three different pathogens. Furthermore, some of the samples were additionally treated with either vitamin A or D. The goal of the study is to identify different gene regulatory patterns, e.g. to figure out the impact of the vitamin treatment upon pathogenic stimulus.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part, Treatment

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accession-icon SRP049028
Human serotonergic neurons
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

Generating human serotonergic neurons from fibroblasts

Publication Title

Generation of functional human serotonergic neurons from fibroblasts.

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE22324
Mapping of disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes
  • organism-icon Homo sapiens
  • sample-icon 200 Downloadable Samples
  • Technology Badge IconIllumina humanRef-8 v2.0 expression beadchip

Description

Analysis of expression quantitative trait loci (eQTLs) using RNA derived from freshly harvested peripheral blood CD4+ lymphocytes from 200 asthmatics collected in clinical settings.

Publication Title

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.

Alternate Accession IDs

E-GEOD-22324

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage, Subject

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accession-icon SRP074108
Ex vivo and In-Cell Mouse Xist SHAPE-MaP
  • organism-icon Mus musculus
  • sample-icon 75 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Ex vivo and in-cell SHAPE-MaP structure probing of the mouse Xist lncRNA.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon E-MEXP-149
Transcription profiling of blasts from three APL patients expressing PML/RAR before and after treatment with 1 uM retinoic acid (RA) in vitro for four hours
  • organism-icon Homo sapiens
  • sample-icon 40 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Description

Gene expression profiles in blasts from three APL patients expressing PML/RAR were assessed before and after treatment with 1 uM retinoic acid (RA) in vitro for four hours. We then studied a U937 clone conditionally expressing PML/RAR (U937-PR), (Grignani et al. 1993) (Alcalay et al. 2003), and compared the gene expression profile prior to and after 4 hours of treatment with 1 uM RA, to that obtained from a cell line bearing an empty vector (U937-MT). For each sample, biotinylated cRNA targets were synthesized starting from 5ug of total RNA, and hybridized to the complete set of HG-U133 Affymetrix oligonucleotide chips, which explores the expression of approximately 45,000 human transcripts. Results were analyzed using MASv5 and further elaborated with the GenePicker software. GeneChip probe sets regulated by RA in each sample were clustered into non-redundant regulated genes according to UniGene release Hs.166.

Publication Title

Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part, Disease, Cell line, Subject, Compound

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accession-icon GSE59896
Gene expression profiling of dectin-1 and NFAT responsive genes in dendritic cells
  • organism-icon Mus musculus
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

This study provides the dectin-1 and NFAT responsive genes for 2h and 4h of curdlan treatment.

Publication Title

NFATc2 mediates epigenetic modification of dendritic cell cytokine and chemokine responses to dectin-1 stimulation.

Alternate Accession IDs

E-GEOD-59896

Sample Metadata Fields

Specimen part

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accession-icon GSE107663
Expression data from hair follicles treated with an osteopontin-derived peptide
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.0 ST Array (hugene20st)

Description

The human hair follicle is not only regulated, but is a source of transcription factors, hormones, neurohormones etc. which are crucial in regulating its growth.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-107663

Sample Metadata Fields

Specimen part

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accession-icon DRP001093
Comprehensive identification of circadian genes in the mouse liver using RNA-Seq
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Comprehensive identification of rhythmically expressed genes in the mouse liver using RNA-Seq

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon DRP001349
Transcriptome of mouse liver in WT and Bmal1 KO mice
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

No description.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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