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accession-icon GSE93586
Expression data from the different EMT and stemness status of lung cancer cell lines
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To study the drug resistant phenotype between stem-like cancer cells at different EMT status, we isolated 4 subpopulations from the non-small-cell lung cancer cell line (PC14) according to the E-cadherin and CD133 expression level. We demonstrated that the epithelial type CD133high stem-like cells (E-cadhighCD133high) significantly exhibited higher drug resistant ability compared to the mesenchymal type CD133high stem-like cells (E-cadlowCD133high), epithelial type CD133low non-stem like cells (E-cadhighCD133low) and mesenchymal type CD133low non-stem like cells (E-cadlowCD133low).

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-93586

Sample Metadata Fields

Cell line

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accession-icon GSE75024
Expression data from Huh7 cells after 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside (PGG) treatment
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

PGG is a natural product exhibits anti-cancer effects on different type of cancers including liver cancer cell lines. In present study we identified a set of genes affected by PGG treatment in Huh7 cells. Some of them, for example, control cell cycle and cell proliferation.

Publication Title

Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma.

Alternate Accession IDs

E-GEOD-75024

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE24976
Amiloride modulates alternative splicing in leukemic cells and re-sensitizes Bcr-AblT315I mutant cells to imatinib
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [probe set (exon) version (huex10st)

Description

We have discovered that amiloride can produce a genome-wide effect on alternative splicing of various RNA transcripts, most importantly including those of the apoptotic factors, in K562 leukemic cells.

Publication Title

Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib.

Alternate Accession IDs

E-GEOD-24976

Sample Metadata Fields

Cell line

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accession-icon GSE18309
Transcriptomes in Peripheral Blood Mononuclear Cells of Dementia and Alzheimer Patients
  • organism-icon Homo sapiens
  • sample-icon 7 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

With the aging population, there is a growing focus on dementia, especially Alzheimers disease (AD). The molecular basis underlying the pathogenesis of AD is gradually being elucidated. Increasing evidence has shown that the immunological function of leukocytes plays a crucial role in the development of neurodegenerative disorders. However, there have been few studies among the Taiwanese population.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-18309

Sample Metadata Fields

Specimen part, Disease, Race

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accession-icon GSE109351
Exon Level Expression Profiling in Kawasaki disease (KD): gene expression profile in healthy control subjects, acute-phase KD subjects and convalescent-phase KD subjects
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Transcriptome analysis of pooled RNA samples from total WBC collection

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-109351

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE6369
Prostate Adenocarcinoma Progression
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Expression profiling of prostate carcinoma tissue samples of benign and metastatic in disease progression.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-6369

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE101879
KK-Ay mice gene expression profile
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

Mouse gene express was using Mouse Gene 1.0 ST Array.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-101879

Sample Metadata Fields

Specimen part

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accession-icon GSE27820
Expression data from active human umbilical cord mesenchymal stem cell (active HUMSC) and inactive human umbilical cord mesenchymal stem cell (inactive HUMSC)
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Active HUMSC with distinct binding rate to MDA MB-231 breast cancer cells, distinct ability in suppressing tumorigenesis,distinct cell in cell features and distinct features under TEM then inactive HUMSC

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-27820

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP115241
Analysis pathogenesis of sudden sensorineural hearing loss (SSNHL) by RNA-seq
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

This study has been approved by the Medical Ethics Committee of the Southern Medical University. Written informed consent was provided by each patient and volunteer before sampling. Nine patients with SSNHL were included in this study, and 3 healthy volunteers were recruited as normal controls.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE52990
Expression data after BCLAF1-L knockdown in human RKO cells
  • organism-icon Homo sapiens
  • sample-icon 1 Downloadable Sample
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Bcl-2-accociated transcription factor 1(BCLAF1) has been reported to be involved in diverse biological processes. Alternative splicing leads to mutiple transcript virants in human cells and we are interested in functions of its full length isoform(BCLAF1-L) in human colon cancer cells, thus to understanding its role in colon cancer progression.

Publication Title

BCLAF1 and its splicing regulator SRSF10 regulate the tumorigenic potential of colon cancer cells.

Alternate Accession IDs

E-GEOD-52990

Sample Metadata Fields

Specimen part, Cell line

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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