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accession-icon SRP091628
Functional disruption of a putative pseudouridine synthase impairs Pi starvation responses in Arabidopsis.
  • organism-icon Arabidopsis thaliana
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

To investigate the molecular mechanism by which the DPS1 mutation affects plant responses to Pi starvation, we performed a comparative RNA sequencing (RNAseq) analysis of the root transcriptomes. Complementary DNA libraries were constructed using the total RNAs isolated from the root of 7-d-old seedlings growing on P+ or P– media.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE27244
Expression profile and whole genome SNP data from acute monocytic leukemia patients
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

Alternate Accession IDs

E-GEOD-27244

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE16925
Expression data from mouse ES and iPS cells
  • organism-icon Mus musculus
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Induced pluripotent stem (iPS) cells were produced from reprogramming of somatic cells, and they are shown to possess pluripotent properties similar to embryonic stem (ES) cells. Here we used microarrays to detail the global expression pattern among the ES cells and iPS cells, as well as the original mouse embryo fibroblast (MEF), to identify important players involved in the reprogramming process.

Publication Title

iPS cells produce viable mice through tetraploid complementation.

Alternate Accession IDs

E-GEOD-16925

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE62078
Expression data from rice panicles of osmads1 mutant and wild type
  • organism-icon Oryza sativa
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

OsMADS1 in rice is an important transcription factor in controlling flower development, not only in flower organs development, but also in floral meristem determinacy. Early flower panicle we used is a high expression stage for OsMADS1.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-62078

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE27187
Expression profile of acute monocytic leukemia patients
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To understand the pathogenesis of DNMT3A in acute monocytic leukemia (AML-M5), we identified genes that are expressed differently in leukemia cells from AML-M5 patients collected at diagnosis with DNMT3A mutations (6 cases) compared to those without the mutations (4 cases). Differences of expression level were observed in 889 out of 20,723 (4.3%) annotated genes by using Affymetrix microarray with 469 genes upregulated and 420 genes downregulated.

Publication Title

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

Alternate Accession IDs

E-GEOD-27187

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE87502
ChIP-seq of intestinal cells and expression profiling of colon tissue after Setd2 disruption
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-87502

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE114419
Coding and Non-coding gene expression signatures of granulosa cells from Polycystic Ovary Syndrome Patients
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Polycystic ovary syndrome (PCOS), one of the most common endocrinal diseases among reproductive-aged women,is characterized by hyperandrogenemia, chronic oligo/anovulation and polycystic ovarian morphology. In this research, we presented microarrays to identify the differential expressed protein-coding genes and lncRNAs expression profile in the luteinized granulosa cells obtained from PCOS and healthy control patients.

Publication Title

Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome.

Alternate Accession IDs

E-GEOD-114419

Sample Metadata Fields

Sex, Specimen part, Disease

View Samples
accession-icon GSE51313
Comparision of gene expression profiles between female germline stem cells and spermatogonia stem cells
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

We used the microarray analysis to compare the globe gene expression profiles of female germ line stem cells (FGSCs) and spermatogonial stem cells (SSCs).

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-51313

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE87500
Changes of misregulated genes in colon tissues after Setd2 disruption
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of expression levels of misregulated genes. Results provide important information of the gene regulation and signaling pathway of setd2.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-87500

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE137354
Coding and Non-coding gene expression signatures of endometrium from Polycystic Ovary Syndrome Patients
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Polycystic ovary syndrome (PCOS), one of the most common endocrinal diseases among reproductive-aged women, is characterized by hyperandrogenemia, chronic oligo/anovulation and polycystic ovarian morphology. In this research, we presented microarrays to identify the differential expressed protein-coding genes and lncRNAs expression profile in the endometrium during the window of implantation between the PCOS and healthy subjects.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-137354

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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