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accession-icon E-MEXP-2681
Transcription profiling by array of muscle biopsies from patients with dermatomyositis or with polymyositis
  • organism-icon Homo sapiens
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Muscle biopsies were taken from 6 patients with dermatomyositis, 4 with polymyositis and 5 not myopathic subjects as controls. The genome-wide expression patterns were compared using Affymetrix HG-U133A chips. Experiment Overall Design: Gene expression profiles were generated for 15 individuals.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage

View Samples
accession-icon E-MEXP-718
Transcription profiling of mouse glioma cell line grown in two types of media to investigate cell de-differentiation
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

Comparison of gene expression profiles of the GL261 cell line (a murine glioma model) grown in duplicate in two different types of media. AC samples where grown in DMEM supplemented by 20% FBS, 5 U/ml pen/strep and 4 mM L-glutamine. NS samples were grown in DMEM/F12 (50/50) supplemented with 2 U/ml pen/strep, 1 ug/ml fungizone, 1x B27, 20 ng/ml bFGF, 20 ng/ml EGF, 20 ng/ml LIF and 5 ug/ml heparin. We have reason to believe the NS media enhances cell de-differentiation.

Publication Title

Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas.

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE104003
Analysis of transcriptome changes arising from MIR205HG modulation in prostate cells
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation.

Alternate Accession IDs

E-GEOD-104003

Sample Metadata Fields

Cell line

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accession-icon GSE76192
RNAPol2 accounts for tumor cells liability to JQ1
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.

Alternate Accession IDs

E-GEOD-76192

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE11701
Genes modulated by miR-205 in DU145 prostate cancer cells
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina humanRef-8 v2.0 expression beadchip

Description

The study was aimed at identifying genes directly or indirectly regulated by miR-205 in the prostate. To this purpose, DU145 prostate cancer cells, which express miR-205 at very low levels, were transfected with miR-205 synthetic precursor and consequent alterations of gene expression analyzed using a microarray approach.

Publication Title

miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.

Alternate Accession IDs

E-GEOD-11701

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE76188
RNAPol2 accounts for tumor cells liability to JQ1 [Affymetrix]
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

We here use B-cell tumors as a model to address the mechanism of action of JQ1, a widely used BET inhibitor.

Publication Title

Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.

Alternate Accession IDs

E-GEOD-76188

Sample Metadata Fields

Treatment

View Samples
accession-icon GSE103655
Effects of deletion of a portion of the Alu element from MIR205HG transcript
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

We aimed at analyzing the transcriptome changes associated with the deletion of a portion of the Alu element from MIR205HG transcript

Publication Title

LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation.

Alternate Accession IDs

E-GEOD-103655

Sample Metadata Fields

Cell line

View Samples
accession-icon GSE103656
Effects of MIR205HG silencing
  • organism-icon Homo sapiens
  • sample-icon 1 Downloadable Sample
  • Technology Badge Icon

Description

We aimed at analyzing the transcriptome changes associated with MIR205HG knock-down in RWPE-1 cells

Publication Title

LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation.

Alternate Accession IDs

E-GEOD-103656

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE37182
Time course analysis of colon cancer samples
  • organism-icon Homo sapiens
  • sample-icon 144 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

Alternate Accession IDs

E-GEOD-37182

Sample Metadata Fields

Specimen part, Disease, Disease stage, Subject, Time

View Samples
accession-icon GSE37175
Time course analysis of colon cancer samples (part 1)
  • organism-icon Homo sapiens
  • sample-icon 60 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

The study outcome was to evaluate the effect of the time on normal colon mucosa samples and possibly select specific genes whose expression is time-related, that could be used as detectors of tissue degradation.

Publication Title

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

Alternate Accession IDs

E-GEOD-37175

Sample Metadata Fields

Specimen part, Disease, Disease stage, Subject, Time

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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