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Homo sapiens
2 Downloadable Samples
Illumina HiSeq 4000
Description
Transcriptomic sequencing of human gastric cancer cell line (AGS) upon citral treatment
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line
View Samples- Arabidopsis thaliana
- 9 Downloadable Samples
- Illumina HiSeq 2000
Description
The study aims to identify differences in gene expression in the root tissue of wild type Columbia-0 as well as Arabidopsis Mediator subunit mutants, med18 and med20 in response to the root pathogen Fusarium oxysporum. Roots were inoculated for 24 hours before harvesting for RNA isolation and paired end Illumina sequencing.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part, Disease, Disease stage, Treatment
View Samples- Rattus norvegicus
- 29 Downloadable Samples
- Illumina HiSeq 2500
Description
Sacha inchi (Plukenetia volubilis L.) extract change the gut microbiota and alleviate the development of hypertension in spontaneously hypertensive rats
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples- Gallus gallus
- 20 Downloadable Samples
- Illumina HiSeq 2500
Description
Male broilers from two lines (n=10 per line) with different growth rate were raised at the same condition with free access to feed and drink. At day 6 and day 21, half samples of each broiler line were euthanized by cervical dislocation, and left ventricles were collected for RNA isolation. Gene expression in left ventricle was measured by RNA-seq and compared between different time points and chicken lines. The purpose of this study is to investigate gene expression change during broiler cardiac development and to compared gene expression between fast-growing modern broilers and slow-growing heritage broilers to find possible genes and pathways related to differential cardiac development and differential susceptibility to cardiac diseases between the two broiler lines.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Disease
View Samples- Gallus gallus
- 8 Downloadable Samples
- Illumina HiSeq 2500
Description
broilers heat stress.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Age, Specimen part
View Samples
SRP115379- Zea mays
- 6 Downloadable Samples
- Illumina HiSeq 2000
Description
We used isolated zygotene meiocytes, corresponding anthers and 2-week-old seedlings from the Zea mays inbred line Mo17 for RNA extraction and library construction for sequencing with Illumina technology to gain insight on gene expression during a key step in meiosis when recombination initiates.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Age, Specimen part
View Samples- Homo sapiens
- 4 Downloadable Samples
- Illumina HiSeq 2500
Description
Dengue virus (DENV) infection causes profound changes in the host cells and these changes underlie the immune response-based viral clearance and pathogenesis. There are several major cell/tissue types relevant for DENV pathogenesis in vivo, including immune cells, liver, and vascular endothelial cells. We applied a directed differentiation system that produces hepatocyte-like cells (HLCs) from pluripotent stem cells to investigate various aspects of DENV- hepatic cells interaction. Human embryonic stem cells were resistant to DENV infection while progeny hepatic cells were permissive. The transition to DENV permissiveness coincided with the upregulation of entry factors for the virus. Infection of HLCs by DENV was self-limiting due to the activation of the interferon (IFN) pathways, which protected by-stander cells from infection but failed to induce the same level of interferon-induced genes (ISGs) expression in the infected cells due to the subversion of IFN signaling by DENV. Innate immunity also protected the infected cells from virus-induced apoptosis. Furthermore, DENV infection activated the NF-?B pathway, increased production of reactive oxidative species (ROS), and led to production of inflammatory cytokines which may contribute to the cytokine storm implicated in dengue hemorrhagic fever (DHF). Finally, DENV infection of HLCs resulted several in vitro phenotypes that may have relevance for acute liver failure and vascular permeability during DHF. These include the disruption of adherens junctions and the downregulation of many liver specific genes such as albumin (ALB) and coagulation factor V (F5).
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Age, Specimen part, Disease, Cell line
View Samples- Pseudomonas aeruginosa
- 4 Downloadable Samples
- Illumina HiSeq 4000
Description
Pseudomonas aeruginosa transcriptomic profile exposed to Cr(VI)
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part, Disease
View Samples- Homo sapiens
- 18 Downloadable Samples
- Illumina HiSeq 2000
Description
We report the biological activity of a Py-Im polyamide targeted to the sequence 5'-WGWWCW-3', which is found in a subset of ARE half-sites. This molecule reduces the growth of enzalutamide-resistant LREX' cells, both in vitro and in vivo. Gene expression changes associated with polyamide treatment in both settings are deposited here.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 4 Downloadable Samples
- Illumina HiSeq 2000
Description
VCaP cells were treated with 10uM of a Py-Im polyamided targeted to the DNA sequence 5''-WGWWCW-3'' for 24hrs. Gene expression changes are normalized to untreated VCaP cells.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples