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accession-icon SRP103200
Enhancer landscape of AML patient samples
  • organism-icon Homo sapiens
  • sample-icon 54 Downloadable Samples
  • Technology Badge Icon

Description

AML patient samples and a few normal blood sample were assayed for H3K27ac ChIP-seq and RNA-seq. We discovered subtypes of AML based on these enhancer landscapes.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP096640
Caenorhabditis elegans LITE-Seq germline 3''UTR sequencing
  • organism-icon Caenorhabditis elegans
  • sample-icon 26 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

LITE-Seq 3'' end capture and sequencing of the C. elegans germline

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon E-MEXP-1112
Transcription profiling of wild type and cli186 mutant Arabidopsis seedlings grown with and without carbon and light to provide information about gene networks regulated by the interaction of light and carbon signaling pathways
  • organism-icon Arabidopsis thaliana
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

This microarray experiment serves to identify the genes in the Arabidopsis genome that are regulated by carbon and light signaling interactions in 7 day dark grown seedlings. The expression profile of wild-type will be compared to the cli186 mutant, a mutant defective in carbon and light signaling. Plants of both the wild-type and cli186 genotypes are treated with the following light (L) and carbon (C) treatments: -C-L, +C-L, +C+L, -C+L. Comparison of the expression profiles under all treatments will help to identify genes that are misregulated in carbon and/or light treatments in the cli186 mutant.

Publication Title

An integrated genetic, genomic and systems approach defines gene networks regulated by the interaction of light and carbon signaling pathways in Arabidopsis.

Alternate Accession IDs

None

Sample Metadata Fields

Age

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accession-icon SRP113255
mRNA sequencing of larval zebrafish heart tissue
  • organism-icon Danio rerio
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

Heart tissue was enriched from 48hpf zebrafish larvae from different experimental conditions. Approximately 200 hearts were collected for each sample. The goals of the study were to profile transcriptional outputs in the cardiac tissue which affects heart development between two different experimental conditions.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP105243
Danio rerio Raw sequence reads
  • organism-icon Danio rerio
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

The goal of the experiment was to simulate the effect of size-selective harvesting and captive rearing on gene expression in a controlled environment using zebrafish as a model species.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP074576
Mus musculus macrophage transcriptome
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Study Goals: To understand the impact of macrophage retention of exosomes on macrophage gene expression and function. Additionally, we also wanted to understand the effect of TLR3 stimulation of HEY cells on exosome mediated macrophage functionsRelevance: Exosomes have a multitude of effects in immunomodulation and cancer cells secrete exosomes that alter the fate of cancer progression. In this study we seek to: 1) understand the effect of TLR stimulation on local cells producing exosomes2) understand the impact of cancer secreted exosomes on cancer progression.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Cell line, Treatment

View Samples
accession-icon SRP074717
Mus musculus breed:Balb/c Transcriptome or Gene expression
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Study goals:To understand the impact of sustained lymph node retention of exosomes on whole lymph node gene expression and function.Relevance: Exosomes have a multitude of effects in immunomodulation and cancer cells secrete exosomes that alter the fate of cancer progression. In this study we seek to: 1) understand the effect of TLR stimulation on local cells producing exosomes 2) understand the impact of cancer secreted exosomes on cancer progression.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Cell line, Treatment

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accession-icon SRP098708
Total RNA-Seq from Starved Drosophila melanogaster
  • organism-icon Drosophila melanogaster
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

Total RNA-Seq from starved Drosophila melanogaster mutant strains fkbp14, trsn, and iso31 control strain.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon SRP148073
Arabidopsis thaliana strain:Col0 | cultivar:Columbia Genome sequencing
  • organism-icon Arabidopsis thaliana
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 3000

Description

MOTHER-OF-FT-AND-TFL1 is a key repressor of seed germination under far-red light in Arabidopsis thaliana

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part, Treatment

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accession-icon SRP068423
Suppression of cancer gene expression by M4N
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

To study the effect of M4N on mRNA expression in human cancer cell

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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