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SRP110865
Saccharomyces cerevisiae
5 Downloadable Samples
Illumina HiSeq 2000
Description
The recombinant S. cerevisiae strains we constructed shown different ability to use xylose and different accumulation of xylitol. To better understand the mechanism of these differences, comparative RNA-seq analysis was conducted between the strains, and the results could further guide us to promote the fermenting property of the recombination strains.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Disease, Cell line
View Samples- Arabidopsis thaliana
- 1 Downloadable Sample
- Illumina HiSeq 2500
Description
to compare the transcriptome between WT and skl1 mutant
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part
View Samples SRP160431- Mus musculus
- 12 Downloadable Samples
- Illumina HiSeq 2500
Description
C2C12 cells, as mouse-derived myoblasts, are a classic cell model for studying skeletal muscle development. We knocked down the immunoglobulin superfamily containing leucine-rich repeat (Islr) gene in C2C12 cell line and studied the effect of Islr on the proliferation and differentiation of C2C12 cells.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Rattus norvegicus
- 3 Downloadable Samples
- Illumina HiSeq 2000
Description
Gene expression profiling analysis reveals ?-3 polyunsaturated fatty acids attenuates a high fat diet induced fatty liver
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
No sample metadata fields
View Samples GSE73024- Homo sapiens
- 65 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Description
Drugs that target specific gene alterations have proven beneficial in the treatment of cancer. Because cancer cells have multiple resistance mechanisms, it is important to understand the downstream pathways of the target genes and monitor the pharmacodynamic markers associated with therapeutic efficacy.
Publication Title
ERK Signal Suppression and Sensitivity to CH5183284/Debio 1347, a Selective FGFR Inhibitor.
Alternate Accession IDs
Sample Metadata Fields
No sample metadata fields
View Samples- Homo sapiens
- 3 Downloadable Samples
- Illumina Genome Analyzer IIx
Description
Exosomes are small membrane vesicles (30-100 nm in diameter) secrted by numerous cells. Exosome have been shown to contain mRNA and DNA. We found at least two types of salivary exosomes (exosome I and exosome II) that are different in size and have different proteome. In previous study, we performed small RNA transcriptome analysis by next generation sequencing technology and reported that many types of small RNA, such as miRNA, piwi-interacting RNA (piRNA), small nucleolar RNA (snoRNA), other small RNAs and genomic repeats were contained in exosome I, II and whole saliva. In this study, we performed whole-transcriptome analysis using cDNA libraries constructed from total RNA except small RNAs. We found that 11-32% of reads from salivary exosomes and whole saliva were mapped to pseudogene. The Data Access Committee of the National Bioscience Database Center (NBDC) approved that this personal genetic data were made published according to NBDC data sharing guidelines (http://humandbs.biosciencedbc.jp/).
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
No sample metadata fields
View Samples- Danio rerio
- 7 Downloadable Samples
- Affymetrix Zebrafish Genome Array (zebrafish)
Description
Effect of ethanol or nicotine exposure on gene expression compared to control. Duplicate arrays from ethanol or nicotine treated animals compared with triplicate arrays from paired control animals. In total 4 treatment arrays (2 ethanol, 2 nicotine) and 3 control arrays (from control animals treated in parallel with ethanol-treated fish and nicotine-treated fish.)
Publication Title
Gene expression changes in a zebrafish model of drug dependency suggest conservation of neuro-adaptation pathways.
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part, Compound
View Samples- Mus musculus
- 54 Downloadable Samples
- Illumina HiSeq 2000
Description
The study aimed to investigate genome-wide transcriptome changes in response to L-lactate in primary neuron cultures.
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Saccharomyces cerevisiae
- 4 Downloadable Samples
- Illumina HiSeq 1000
Description
Transcriptome sequencing of wild-type and Rad30 knockout strains under normal conditions and 2 mM H2O2 conditions to study physiological mechanisms of the gene Rad30 response to oxidative stress
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Specimen part, Disease, Cell line
View Samples- Mus musculus
- 6 Downloadable Samples
- Illumina HiSeq 2500
Description
Understanding host-pathogen interactions in tuberculosis is essential to d develop strategies and therapeutic tools to control Mycobacterium tuberculosis (Mtb). In this study, we performed the transcriptome analyses of macrophages infected with virulent Mtb strain H37Rv (Rv) or avirulent Mtb strain H37Ra (Ra).
Publication Title
No associated publication
Alternate Accession IDs
None
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples