No description.
No associated publication
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Sex, Specimen part, Cell line, Treatment
View SamplesStudy of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.
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Specimen part, Cell line, Compound
View SamplesWe propose a microfluidic strategy to generate abundant brain organoids and further explore neurogenesis in fetal brain exposed to ethanol.
No associated publication
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Sex, Specimen part, Disease, Cell line, Treatment
View SamplesT cell lymphoma
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
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Sex, Specimen part, Cell line
View SamplesP19 differentiating cells were spread a two densities and mRNA from the two densities were compared
No associated publication
None
Cell line
View SamplesGrapevines are easy to be attacked by Erysiphe necator, so it is significant to uncover why Chinese wild Vitis pseudoreticulata has strong resistance to such a common fungi, which can provide guidance for breeding disease resistance grapevine varieties. This project is aimed to unravel the defense mechanism of Chinese wild Vitis pseudoreticulata to Erysiphe necator on posttranscriptional level mediated by microRNAs. To profile the microRNA expression affected by Erysiphe necator infection and identify microRNAs relative to powdery mildew resistance, two sRNA libraries were constructed from inoculated and non-inoculated grapevine leaves for small RNA high throughput sequencing.
No associated publication
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Sex, Specimen part, Cell line, Treatment
View SamplesTo test the "one-neuron-one-receptor" rule of olfactory receptor expression, we sequenced the transcriptomes of single olfactory sensory neurons from the main olfactory epithelium of adult (1 to 3 months) and newborn mice (postnatal day 4 to 10).
No associated publication
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Sex, Specimen part, Cell line
View SamplesWe report the biological activity of a Py-Im polyamide targeted to the sequence 5'-WGWWCW-3', which is found in a subset of ARE half-sites. This molecule reduces the growth of enzalutamide-resistant LREX' cells, both in vitro and in vivo. Gene expression changes associated with polyamide treatment in both settings are deposited here.
No associated publication
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Sex, Specimen part, Cell line
View SamplesVCaP cells were treated with 10uM of a Py-Im polyamided targeted to the DNA sequence 5''-WGWWCW-3'' for 24hrs. Gene expression changes are normalized to untreated VCaP cells.
No associated publication
None
Sex, Age, Specimen part, Cell line
View SamplesThis study addresses long-term effects of clinically relevant regimens of radiation in human glioma stem cells. Our investigations reveal a strikingly diverse spectrum of changes in cell behavior, gene expression patterns and tumor-propagating capacities evoked by radiation in different types of glioma stem cells. Evidence is provided that degree of cellular plasticity but not the propensity to self-renew is an important factor influencing radiation-induced changes in the tumor-propagating capacity of glioma stem cells. Gene expression analyses indicate that paralell transcriptomic responses to radiation underlie similarity of clinically relevant cellular outcomes such as the ability to promote tumor growth after radiation. Our findings underscore the importance of longitudinal characterizations of molecular and cellular responses evoked by cytotoxic treatrments in glioma stem cells.
Diversity of Clinically Relevant Outcomes Resulting from Hypofractionated Radiation in Human Glioma Stem Cells Mirrors Distinct Patterns of Transcriptomic Changes.
Treatment
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