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accession-icon SRP148483
Transcriptome data of flower bud distortion in witches' broom disease of soybean (Glycine max) variety JS-335 (R5 stage)
  • organism-icon Glycine max
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

No description.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP132246
RNA- Seq analysis of soybean varieties during early stages of charcoal rot infection
  • organism-icon Glycine max
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The RNA-Seq analysis of charcoal rot infection in two soybean genotypes during the initial infection. The study would provide insights into the genetic re-programming of transcriptome, following infection.

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

Age, Specimen part, Disease, Treatment

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accession-icon GSE45220
Expression data from HT-29, a human colonic epithelial cell line
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.1 ST Array (hugene11st)

Description

Gene(s) in epithelial cells can be upregulated or downregulated by different stimuli in a tissue-specific manner. We used genome-wide microarray analysis to profile the expression of genes in HT-29 cells that are upregulated after stimulation with sodium butyrate (NaB) and subsequently downregulated by the addition of ciprofloxacin antibiotic. The specific aim was to evaluate genes that are associated with mucosal immunity.

Publication Title

No associated publication

Alternate Accession IDs

E-GEOD-45220

Sample Metadata Fields

Specimen part, Cell line, Treatment

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accession-icon E-ATMX-30
Transcription profiling by array of Arabidopsis mutant for AtMYB44 or overexpressing AtMYB44 under the control of the 35S promoter after treatment with NaCl
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

screening of AtMYB44-responsive genes under 250mM NaCl treatment

Publication Title

Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis.

Alternate Accession IDs

None

Sample Metadata Fields

Compound

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accession-icon E-ATMX-4
Transcription profiling of wild type and JMT over-expressing Arabidopsis plants
  • organism-icon Arabidopsis thaliana
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis Genome Array (ag)

Description

Effect of JMT overexpression in global gene expression

Publication Title

Complement analysis of xeroderma pigmentosum variants.

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP062685
Danio rerio Transcriptome or Gene expression
  • organism-icon Danio rerio
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

Differential Expression between testis and ovary in two months of fish

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP062686
Danio rerio Digital Gene Expression Sequencing
  • organism-icon Danio rerio
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

Differential expression between WT and CD82a from Morpholino-treated embyro of Danio rerio

Publication Title

No associated publication

Alternate Accession IDs

None

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE53473
Standard of hygiene and immune adaptation in newborn infants
  • organism-icon Homo sapiens
  • sample-icon 128 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U219 Array (hgu219)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Standard of hygiene and immune adaptation in newborn infants.

Alternate Accession IDs

E-GEOD-53473

Sample Metadata Fields

Sex

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accession-icon GSE53471
Standard of hygiene and immune adaptation in newborn infants [113 cord blood RNA samples]
  • organism-icon Homo sapiens
  • sample-icon 113 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U219 Array (hgu219)

Description

The prevalence of immune-mediated diseases such as allergies and autoimmune diseases is on the rise in the developed world. Microbial exposure is known to modulate the risk for these diseases. In order to explore differences in the gene expression patterns induced in utero in infants born in contrasting standards of living and hygiene, we collected umbilical cord blood RNA samples from full-term newborn infants born with normal vaginal delivery in Finland (modern society), Estonia (rapidly developing society) and the Republic of Karelia, Russia (poor economical conditions). Transcriptomic profiles were analyzed using whole genome microarrays including gender, gestational age, birth month and HLA allele genotype as confounding variables in the analysis. The data revealed that the whole blood transcriptome of Finnish and Estonian neonates differ from their Karelian counterparts. Samples from Karelian infants had an increase in transcripts associated with LPS induction and bacterial sepsis observed in 1-year-old infants in earlier studies. The results suggest exposure to toll like receptor (TLR) ligands and a more matured immune response in infants born in Petrozavodsk compared to the Finnish and Estonian infants. These results further support the concept of a conspicuous plasticity in the developing immune system: the environmental factors that play a role in the susceptibility/protection towards immune-mediated diseases begin to shape the neonatal immunity already in utero and direct the maturation of both the adaptive and the innate immune responses in accordance with the surrounding microbial milieu.

Publication Title

Standard of hygiene and immune adaptation in newborn infants.

Alternate Accession IDs

E-GEOD-53471

Sample Metadata Fields

Sex

View Samples
accession-icon GSE17241
Genome-wide analysis of SATB1 target genes in human T helper cells
  • organism-icon Homo sapiens
  • sample-icon 46 Downloadable Samples
  • Technology Badge IconSentrix Human-6 Expression BeadChip

Description

Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer and a transcription factor induced by interleukin-4 (IL-4) during the early T helper 2 (Th2) cell differentiation. In this study, we investigated the role of SATB1 in T helper cell differentiation by performing gene expression profiling of human differentiating Th cells in which expression of SATB1 was downregulated by RNA interference (RNAi). Our results indicate that SATB1 is involved in the regulation of more than three hundred genes in primary human CD4+ T cells, including several IL-12 and/or IL-4 regulated factors, suggesting a role in the development or function of Th subtypes.

Publication Title

SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation.

Alternate Accession IDs

E-GEOD-17241

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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