Description

Alterations in gene expression following fatty acid synthase inhibtion were evaluated in androgen sensitive LNCaP cells and castration resistant 22Rv1 and LNCaP-95 cells. Cell were exposed to 2 concentrations (0.1 and 0.5 uM) of FASN inhibitor IPI-9119 or DMSO for 6 days. Overall design: Differential gene expression anlaysis in 3 prostate cancer cell lines treated with FASN inhibitor IPI-9119

Publication Title

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.

Alternate Accession IDs

GSE114016

Sample Metadata Fields

Specimen part, Cell line, Subject