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accession-icon E-TABM-304
Transcription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

Transcription profiling by array of pancreas from KrasG12D, Ela-Tgfa and KrasG12D Ela-Tgfa mice

Publication Title

Concomitant pancreatic activation of Kras(G12D) and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN.

Alternate Accession IDs

None

Sample Metadata Fields

Age, Specimen part

View Samples
accession-icon GSE10714
Expression data from human colonic biopsy sample
  • organism-icon Homo sapiens
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Gene expression profile based classification of colonic diseases are suitable for identification of diagnostic mRNA expression patterns which can establish the basis of a new molecular biological diagnostic method

Publication Title

Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results.

Alternate Accession IDs

E-GEOD-10714

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE10715
Expression data from normal and CRC human peripheral blood samples
  • organism-icon Homo sapiens
  • sample-icon 29 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The whole-genome oligonucleotide microarray analysis of peripheral blood samples can contribute to the determination of distant blood markers of local pathophysiological alterations in colorectal diseases. These markers can lead to alternative screening procedures.

Publication Title

Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results.

Alternate Accession IDs

E-GEOD-10715

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE15960
Expression data from human colonic epithelial cells normal (N), adenoma (AD) or colorectal cancer (CRC) tissues
  • organism-icon Homo sapiens
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The whole-genome oligonucleotide microarray analysis of laser microdissected human colonic epithelial cells can contribute to determination of disease-specific expression alterations in colonic epithelial cells and to localize the origin the expression changes measured in whole biopsy samples.

Publication Title

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.

Alternate Accession IDs

E-GEOD-15960

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE15799
Expression data from NS398-treated and control HT29 colon adenocarcinoma cell line samples
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The whole-genome oligonucleotide microarray analysis of NS398-treated HT29 colon adenocarcinoma cells samples can give an insight into global molecular background of selective COX2 inhibitor administration in order to find other target molecules and pathways influenced by NS398 selective COX2 inhibitor treatment in the epithelial cells.

Publication Title

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor.

Alternate Accession IDs

E-GEOD-15799

Sample Metadata Fields

Cell line, Treatment

View Samples
accession-icon GSE29060
Expression data from human HT-29 immortalized colorectal adenocarcinoma cell line
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Gene expression profiling for identification of genes regulated by DNA methylation

Publication Title

Genome-wide screening of genes regulated by DNA methylation in colon cancer development.

Alternate Accession IDs

E-GEOD-29060

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE37364
Expression data from human colonic biopsy samples (adenoma-carcinoma)
  • organism-icon Homo sapiens
  • sample-icon 91 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Whole genomic microarray analysis was performed in order to identify gene expression profile alterations focusing on the dysplastic adenoma-carcinoma transition. Our aims were to determinate characteristic transcript sets for developing diagnostic mRNA expression patterns for objective classification of benign and malignant colorectal diseases and to test the classificatory power of these markers on an independent sample set.

Publication Title

Myofibroblast-derived SFRP1 as potential inhibitor of colorectal carcinoma field effect.

Alternate Accession IDs

E-GEOD-37364

Sample Metadata Fields

Disease, Disease stage

View Samples
accession-icon GSE5081
Expression data from Helicobacter positive and negative human gastritis samples
  • organism-icon Homo sapiens
  • sample-icon 32 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The whole-genome oligonucleotide microarray analysis gives an opportunity for studying the unidentified gene expression background of the idiopathic and H.pylori related gastric erosive alterations. Using microarrays we compared the whole genome gene expression profile of HP+ and HP- gastric erosions and normal adjacent mucosa to explain the possible role and response to HP infection and to get morphology related mRNA expression patterns.

Publication Title

Helicobacter pylori and antrum erosion-specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts.

Alternate Accession IDs

E-GEOD-5081

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon GSE87287
mRNA exrpession patterns in response to RelA siRNA
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

The experiment aims to identify mRNAs regulated in response to RelA

Publication Title

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer.

Alternate Accession IDs

E-GEOD-87287

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE61256
Obesity accelerates epigenetic aging of human liver
  • organism-icon Homo sapiens
  • sample-icon 133 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.1 ST Array (hugene11st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Obesity accelerates epigenetic aging of human liver.

Alternate Accession IDs

E-GEOD-61256

Sample Metadata Fields

Sex, Age, Disease, Subject

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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