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accession-icon GSE42997
The ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

We investigate the role of Snf2l in ovaries by characterizing a mouse bearing an inactivating deletion on the ATPase domain of Snf2l (Ex6DEL). Snf2l mutant mice produce significantly fewer eggs than control mice when superovulated. Thus, gonadotropin stimulation leads to a significant deficit in secondary follicles and an increase in abnormal antral follicles. We profiled the expression of granulosa cells from Snf2l WT and Ex6DEL mice treated with pregnant mares' serum gonadotropin followed by human chorionic gonadotropin

Publication Title

The imitation switch ATPase Snf2l is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells.

Alternate Accession IDs

E-GEOD-42997

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE29759
The Role of microRNAs in Neural Stem Cell-supported Endothelial Morphogenesis
  • organism-icon Mus musculus
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

MicroRNA microarrays and RNA expression arrays were used to identify functional signaling between neural stem cell progenitor cells (NSPC) and brain endothelial cells (EC) that are critical during embryonic development and tissue repair following brain injury.

Publication Title

The role of microRNAs in neural stem cell-supported endothelial morphogenesis.

Alternate Accession IDs

E-GEOD-29759

Sample Metadata Fields

Specimen part, Disease, Treatment

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accession-icon GSE35766
Identification of the cortical neurons that mediate antidepressant responses
  • organism-icon Mus musculus
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35766

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE20854
EGFR Isoforms and Gene Regulation in Human Endometrial Cancer Cells
  • organism-icon Homo sapiens
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Microarrays were used to analyze differential gene expression and to help determine the efficacy of Iressa (gefitinib), a tyrosine kinase inhibitor, on endometrial cancer cells.

Publication Title

EGFR isoforms and gene regulation in human endometrial cancer cells.

Alternate Accession IDs

E-GEOD-20854

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE18235
Effect of 10 Cigarette Smoke Condensates on Primary Human Airway Epithelial Cells
  • organism-icon Homo sapiens
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Nine cigarette smoke condensates (CSCs) were produced under a standard ISO smoking machine regimen and one was produced by a more intense smoking machine regimen. These CSCs were used to treat primary normal human bronchial epithelial cells for 18 hours.

Publication Title

Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies.

Alternate Accession IDs

E-GEOD-18235

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE35758
Comparative analysis of S100a10 and Glt25d2 cortical pyramidal cells
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows robust and specific molecular adaptations following long-term SSRI treatment.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35758

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE35751
Comparative analysis of S100a10-expressing cortical pyramidal cells and whole cortex
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows robust and specific molecular adaptations following long-term SSRI treatment.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35751

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE35761
Effect of fluoxetine treatment on translational profiles of S100a10 cortical pyramidal cells
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows robust and specific molecular adaptations following long-term SSRI treatment.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35761

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE35763
Effect of fluoxetine treatment on translational profiles of Glt25d2 cortical pyramidal cells
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows robust and specific molecular adaptations following long-term SSRI treatment.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35763

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE35765
Effect of fluoxetine treatment on translational profiles of S100a10 cortical pyramidal cells in p11 KOs
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows robust and specific molecular adaptations following long-term SSRI treatment.

Publication Title

Identification of the cortical neurons that mediate antidepressant responses.

Alternate Accession IDs

E-GEOD-35765

Sample Metadata Fields

Specimen part, Treatment

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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