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Accession IconSRP186643

A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution

Organism Icon Caenorhabditis elegans
Sample Icon 55 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
We sequence the transcriptomes of 86,024 single cells from C. elegans embryos, spanning from gastrulation to the beginning of cuticle synthesis. We identify the lineage (from the invariant C. elegans cell lineage) and approximate developmental age of each cell in the single cell data. Using these annotations, we investigate the competing influences of cell lineage and cell fate on gene expression. Overall design: Single cell RNA-seq profiles of cells from C. elegans embryos at varying developmental stages (~100-650 minutes post first cleavage).
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