Effect of DKK1 on embryo elongation

We report the effect of DKK1 treatment during culture on the length and transcriptome of embryos on day 15 of development, supporting the notion that changes early in development affect later stages of development. Overall design: Bovine embryos were produced in vitro and exposed to either 0 or 100 ng/ml DKK1 from day 5 to 7 of culture. Embryos were transferred on day 7 and recovered on day 15 for evaluation of length and transciptome

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Tríbulo P, Rabaglino MB, Bo MB, Carvalheira LR, Bishop JV, Hansen TR, Hansen PJ