Transcriptome analysis of mdx hearts and skeletal muscles treated with cardiac progenitor cells and their exosomes

Aged mdx mice were treated with 2.5x105 cardiosphere-derived cells (CDCs) or 2.0x109 exosomes intravenously. Hearts and skeletal muscles were harvested 3 weeks post-treatment and prepared for RNA sequencing. Overall design: Comparison of transcriptomic changes in mdx hearts and skeletal muscles by cardiac progenitor cell and exosome treatments

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Rogers RG, Fournier M, Sanchez L, Ibrahim AG, Aminzadeh MA, Lewis MI, Marbán E