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Accession IconSRP171145

Effects of losmapimod on non-specific inflammatory response in aged skin.

Organism Icon Homo sapiens
Sample Icon 30 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
We have previously demonstrated older skin exhibits increased sterile inflammation 6 hours after saline-injection. In this work, we examined whether p38MAPK inhibitor in vivo would attenuate this non-specific inflammatory response towards saline in elder individuals (=65 years). Overall design: Skin mRNA profiles 6 hours after saline injection were studied before and after losmapimod treatment.
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