mRNA-seq for etoposide-treated TLP-knockdown cells

We explored the mechanism by which TLP affects DNA damage response. We performed mRNA-seq analysis of non-treated and etoposide-treated samples in control and TLP-knockdown cells. We show that TLP is critical for global transcriptional repression after double-strand DNA breaks (DSBs). Overall design: Examination of non-treated and etoposide-treated samples in control and TLP-knockdown cells

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Suzuki H, Okamoto-Katsuyama M, Suwa T, Maeda R, Tamura TA, Yamaguchi Y