Expression profiling of NRAS knockout in embryonal rhabdomyosarcoma (ERMS) cells

Targeted disruption of NRAS was performed in a stable 381T ERMS cell line harboring tamoxifen inducible CRISPR/Cas9 gRNA against NRAS Overall design: RNA sequencing was performed using RNA extracted from uninduced control 381T ERMS cells as well as tamoxifen (TAM)-induced ERMS cells with NRAS CRISPR/Cas9-mediated knockout. Each in 3 biological replicates.

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Phelps MP, Yang H, Patel S, Rahman MM, McFadden G, Chen E