Lin28/let-7 axis regulates the timig of cession of nephrogenesis

To study role of Lin28/let-7 axis on nephrogenesis, we profiled kidney transcriptom of LIN28 OE, let-7 KO, and their wild-type littermate control mice. Overall design: RNA-seq on kidneys from LIN28B OE, let-7 KO, and their wild-type littermate controls at P3.

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Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ