RNA-sequencing analysis of differentially expressed genes (DEGs) induced by STC2 overexpression in colorectal cancer cells

To identify STC2-regulated downstream target genes, we compared the results of RNA-seq analysis between colorectal cancer cells without STC2 (SW480-NC) and cells with STC2 (SW480-STC2). Overall design: Colorectal cancer cells SW480 were transfected with negative control (named SW480-NC) or STC2 overexpression vectors (named SW480-STC2). Then cells were harvested for RNA isolation for RNA-seq analysis.

2

Wang J, Sahengbieke S, Xu X, Zhang L, Xu X, Sun L, Deng Q, Wang D, Chen D, Pan Y, Liu Z, Yu S