Gene expression in WT and Thpok-deficient LCMV-specific memory T cells

Gene expression of memory CD4+ and CD8+ T cells determined by RNAseq 30 days after LCMV Armstrong infection Overall design: 30 days post-infection with LCMV Arm spleen GP66:I-Ab+ T cells from Zbtb7bAD (CD4 Zbtb7bAD) or Tnfrsf4-Cre– (CD4 Ctrl) mice and of spleen GP33:H-2Db+ T cells from Tnfrsf4-Cre– animals (CD8 Ctrl) were sorted and gene expression was determined by RNAseq

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Ciucci T, Vacchio MS, Gao Y, Tomassoni Ardori F, Candia J, Mehta M, Zhao Y, Tran B, Pepper M, Tessarollo L, McGavern DB, Bosselut R