Trans-differentiation of human adult peripheral blood T cells into neurons

Examining the transcriptomic changes during transdifferentiation of peripheral blood mononuclear cells to induced neuronal cells. Overall design: There are three different populations: PBMC (2 biological replicates, starting population), PSA-NCAM+GFP+ (2 biological replicates, induced neuronal cells) and PSA-NCAM+GFP- (2 biological replicates, induced neuronal cells).

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Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M