Global alternative splicing analysis of cryptic splicing suppressors in C. elegans

SRP140694

Caenorhabditis elegans

No Downloadable Samples

Illumina HiSeq 4000

Submitter Supplied Information

Description

Dominant mutant alleles of prp-8 and snrp-27 were identifed in a forward genetic screen for suppressors of cryptic splice site activation Overall design: Strains with cryptic splicing suppressor mutations in prp-8 and snrp-27 were compared to wild type strains to identify changes in native gene alternative splicing

PubMed ID

30006499

Publication Title

SNRP-27, the <i>C. elegans</i> homolog of the tri-snRNP 27K protein, has a role in 5' splice site positioning in the spliceosome.

Total Samples

Submitter’s Institution

No associated institution

Authors

Zahler AM, Rogel LE, Glover ML, Yitiz S, Ragle JM, Katzman S

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE113275

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