Tissue damage signaling is essential for protective neutrophil recruitment to microbial infection in zebrafish (Danio rerio)

RNAseq was performed on zebrafish larvae infected with bacteria under different osmotic pressures. The trascriptome profile generated here reveals the differential immune gene expression pattern. Overall design: Pseudomonas aeruginosa resuspended in either standard or isotonic E3 were injected into the otic vesicle of zebrafish larvae. Uninjected zebrafish larvae served as control. Total RNA was extracted after 1 hour of infection and processed to following sequencing.

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Huang C, Niethammer P