Transcriptional changes of serum stimulation in mouse embryonic fibroblasts due to loss of PIN1

SRP131098

Mus musculus

4 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

The goal of this study was to determine the transcriptional difference between WT and PIN1 knockout mouse embryonic fibroblasts. Overall design: Wildtype and PIN1 knockout MEFs were serum starved for 48 hours, and stimulated 4hrs to induce MYC expression. RNA was harvested from 2 independent experimental replicates per genotype.

PubMed ID

30366908

Publication Title

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals.

Total Samples

Submitter’s Institution

No associated institution

Authors

Su Y, Pelz C, Huang T, Torkenczy K, Wang X, Cherry A, Daniel CJ, Liang J, Nan X, Dai MS, Adey A, Impey S, Sears RC

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE109457

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