Genetic dissection of chromatin regulators reveals the INO80 chromatin remodeling complex as a key metabolic regulator utilizing TORC1 and histone acetylation pathways

SRP117072

Saccharomyces cerevisiae

No Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We performed RNA-seq in wild-type yeast, a strain lacking INO80, and a strain lacking ARP5, central components of the INO80 chromatin remodelling complex, treated with rapamycin Overall design: Yeast mRNA profiles were generated for WT, arp5, ino80 mutant strains treated with rapamycin

PubMed ID

29462149

Publication Title

The INO80 chromatin remodeler sustains metabolic stability by promoting TOR signaling and regulating histone acetylation.

Total Samples

Submitter’s Institution

No associated institution

Authors

Beckwith SL, Schwartz EK, García-Nieto PE, King DA, Gowans GJ, Wong KM, Eckley TL, Paraschuk AP, Peltan EL, Lee LR, Yao W, Morrison AJ

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE103468

No rows found