Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells

SRP112521

Homo sapiens

9 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

Differential expression patterns of total mRNA in traditionally expanded T cells (vehicle) compared to T cells expanded under drugs (AKT inhibitor and CAL-101) Overall design: Comparison of transcriptional effects of two different drugs

PubMed ID

29033940

Publication Title

PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8<sup>+</sup> T Cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

Bowers JS, Majchrzak K, Nelson MH, Aksoy BA, Wyatt MM, Smith AS, Bailey SR, Neal LR, Hammerbacher JE, Paulos CM

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE101497

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