TonEBP/NFAT5 controls inflammatory transcriptional response to TNF-a in nucleus pulposus cells

SRP103733

Rattus norvegicus

12 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

RNA sequencing of nucleus pulposus cells transduced with shRNA (control or TonEBP-targeted) and either untreated or treated with TNF-a (24h) Overall design: Total mRNA was collected from primary nucleus pulposus cells and subjected to RNA sequencing, n=3 for all experimental groups

PubMed ID

28842479

Publication Title

TNF-α promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

Johnson ZI, Doolittle AC, Snuggs JW, Shapiro IM, Le Maitre CL, Risbud MV

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE97496

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