Differential expression analysis of haploid, diploid, and tetraploid yeast experimentally evolved in raffinose medium

Haploid, diploid, and tetraploid yeast were experimentally evolved in 2% raffinose medium. After 250 generations, we assessed the gene expression alterations in 2 evolved haploids, 2 evolved diploids, and 4 evolved tetraploids relative to the diploid ancestor. Overall design: mRNA gene expression profiles of 2 evolved haploid, 2 evolved diploid, and 4 evolved tetraploid clones were compared to the expression profile of the diploid ancestral strain in 2% raffinose medium.

9

Scott AL, Richmond PA, Dowell RD, Selmecki AM