Transcriptome characterization of human periodontal ligament cell clones (DMEM medium)

In this study, we purified periodontal ligament cell clones committed to osteoblastic/cementoblastic phenotype (C-O clones) and clones committed to fibroblastic phenotype (C-F clones), and employed RNA-seq to describe the differential transcriptional profile of osteoblastic/cementoblastic and fibroblastic cell clones from human periodontal ligament. The understanding of differences in periodontal ligament subpopulations can help to elucitade the favorable to formation of mineralizing and non-mineralizing tissues of periodontium.

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