Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [patients RNA-Seq]

SRP095948

Homo sapiens

5 Downloadable Samples

NextSeq 500

Submitter Supplied Information

Description

The goal of this study is to investigate if endogenous RNA in exosomes activates RIG-I through unshielding. Overall design: transcription profiling of exosomal RNA isolated from breast cancer patients before, during and after radiation therapy.

PubMed ID

28709002

Publication Title

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

Total Samples

Submitter’s Institution

No associated institution

Authors

Nabet BY, Qiu Y, Shabason JE, Wu TJ, Yoon T, Kim BC, Benci JL, DeMichele AM, Tchou J, Marcotrigiano J, Minn AJ

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE93072

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