Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [exoRNA-Seq]

SRP095943

Homo sapiens

4 Downloadable Samples

NextSeq 500

Submitter Supplied Information

Description

The goal of this study is to investigate if endogenous RNA in exosomes activates RIG-I through unshielding. Overall design: transcription profiling for exosomal RNA isolated from stroma cell (MRC5) or stroma/breast cancer cell co-culture (MRC5 and 1833).

PubMed ID

28709002

Publication Title

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.

Total Samples

Submitter’s Institution

No associated institution

Authors

Nabet BY, Qiu Y, Shabason JE, Wu TJ, Yoon T, Kim BC, Benci JL, DeMichele AM, Tchou J, Marcotrigiano J, Minn AJ

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE93070

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