Gene expression profile of regulatory T cell (Treg) subsets from CD28-deficient mouse

SRP095091

Mus musculus

18 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

A comparative analysis of gene expression of CD4+ EGFP+ Nrp1+ (tTreg, thymus-derived Treg), CD4+ EGFP+ Nrp1- (pTreg, peripherally-derived Treg) and CD4+ EGFP- (Tconv, conventional T cell) in CD28-/- Foxp3EGFP and Foxp3EGFP mice. Overall design: Nrp1+ Treg (tTreg), Nrp1- Treg (pTreg) and Tconv were sorted from Foxp3EGFP and CD28-/-Foxp3EGFP mice. Total RNAs were extracted from whole samples and analyzed by RNA-seq.

PubMed ID

29425339

Publication Title

CD28 co-stimulation is dispensable for the steady state homeostasis of intestinal regulatory T cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

Wakamatsu E, Omori H, Tabata Y, Akieda Y, Watanabe S, Ogawa S, Abe R

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE92376

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