Requirements for different Tcf1 isoforms in T cell development

SRP095021

Mus musculus

6 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

Comparison of transcriptome between control, Tcf1 long isoform (p45)-deficient, complete Tcf1-deficient DN3 thymoctyes Overall design: lineage-negative, CD4-, CD8-, CD44 low and CD25 high (DN3) thymocytes were sorted from control mice or those are deficient for either Tcf1 long isoforms (p45) or all Tcf1 proteins. Lck-Cre was used to ablate all Tcf1 proteins

PubMed ID

28348272

Publication Title

Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.

Total Samples

Submitter’s Institution

No associated institution

Authors

Xu Z, Xing S, Shan Q, Gullicksrud JA, Bair TB, Du Y, Liu C, Xue HH

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE92323

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