LIN-28 balances longevity and germline stem cell number in C. elegans through let-7/AKT/DAF-16 axis

Transcriptomic effects of lin-28 RNAi on N2 and glp-1 worms were compared. Overall design: RNA samples of N2 and glp-1 worms on adult day 4 under empty vector (EV) or lin-28 RNAi from L1 were sequenced.

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Wang D, Hou L, Nakamura S, Su M, Li F, Chen W, Yan Y, Green CD, Chen D, Zhang H, Antebi A, Han JJ