Age and diet affect genetically separable secondary injuries that cause acute mortatlity following traumatic brain injury in Drosophia

To identify genes involved in TBI outcomes in Drosophila we compared genome-wide mRNA expression of uninjured and injured flies under both age and diet conditions. Overall design: Whole male fly mRNA profiles of 0-7 day and 20-27d old Drosophila line w1118 were generated, with or without injury and under two different dietary conditions. Experiments were preformed in triplicate, using Illumina HiSeq 2500.

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Katzenberger RJ, Ganetzky B, Wassarman DA