Transcriptome comparison of oocytes treated with RNAi against Btg4 or with control siRNAs

The comparison of trancriptomes was part of the study by Pasternak et al. The goal was to check if BTG4 regulates mRNA polyadenylation during mouse oocyte meiosis. To test this we compared the abundancies of the polyadenylated trancripts in control and Btg4-depleted oocytes. Overall design: 3 samples of 50 oocytes were collected for both groups

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Pasternak M, Pfender S, Santhanam B, Schuh M