Transcriptional profiling of parental mouse erythroleukemia (MEL) and HMBA-resistant (MEL-R) cells

We have previously isolated a murine erythroleukemia cell line refractive to re-enter a cell differentiation program as opposite to the progenitor cell line. We use RNA-seq to identify differentially expressed genes in both cell lines Overall design: Gene expression levels from MEL DS19 and MEL-R cell cultures were compared by next generation sequencing using standard RNA-seq protocols

12

Fernández-Calleja V, Hernández P, Schvartzman JB, García de Lacoba M, Krimer DB