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Accession IconSRP075646

RNA-sequencing in WT and Fmr1-/- (KO) neurons treated with Jq1 and THZ

Organism Icon Mus musculus
Sample Icon 18 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
Widespread epigenetic disruptions in FXS mice leads to transcriptional changes that likely contribute to the neuronal phenotpyes underlying FXS. Overall design: 7DIV cultured cortical neurons from WT or Fmr1 KO mice were treated for 24 hours with vehicle, Jq1, or THZ, performed in triplicate.
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18
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