Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity.

SRP075118

Homo sapiens

36 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

RNA-sequencing was performed on human CD19- CD138+ bone marrow plasma cells. Overall design: 4 biological replicates of human CD19- CD138+ bone marrow plasma cells and 1 replicate each of naÃ¯ve, IgM memory, IgG memory, and plasmablasts from peripheral blood.

PubMed ID

27396958

Publication Title

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

Lam WY, Becker AM, Kennerly KM, Wong R, Curtis JD, Llufrio EM, McCommis KS, Fahrmann J, Pizzato HA, Nunley RM, Lee J, Wolfgang MJ, Patti GJ, Finck BN, Pearce EL, Bhattacharya D

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE81443

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