Transcriptome-wide mRNA alterations in Streptozotocin induced Type I diabetic mouse heart

SRP074888

Mus musculus

5 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We sequenced mRNA from Left Ventricles of Streptozotocin induced Type I diabetic mouse hearts or mock treated controls at 4 weeks post-treatment in order to assess alternative splicing changes. Overall design: Heart mRNA profiles of Control and Diabetic (STZ:T1D) mice were generated by deep sequencing using Illumina HiSeq 1000.

PubMed ID

27239029

Publication Title

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes.

Total Samples

Submitter’s Institution

No associated institution

Authors

Nutter CA, Jaworski EA, Verma SK, Deshmukh V, Wang Q, Botvinnik OB, Lozano MJ, Abass IJ, Ijaz T, Brasier AR, Garg NJ, Wehrens XHT, Yeo GW, Kuyumcu-Martinez MN

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE80664

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