RNA Sequencing Facilitates Quantitative Analysis of Primary Microglia Transcriptomes II

SRP073328

Mus musculus

9 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Using RNA-seq, we report here that primary microglia (PM) cells have a distinct transcriptomic signature and express a unique cluster of transcripts in response to 2hrs or 4 hrs with LPS. Overall design: Examination of effects of LPS-stimulated PM microglial cells, were generated by deep sequencing on an Illumina HiSeq 2000(101 cycles PE lane).

PubMed ID

27400875

Publication Title

Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia.

Total Samples

Submitter’s Institution

No associated institution

Authors

Das A, Kim SH, Arifuzzaman S, Yoon T, Chai JC, Lee YS, Park KS, Jung KH, Chai YG

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE80304

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