Transcriptome analysis of condensin II knockdown cells

SRP073037

Mus musculus

4 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

Condensin complexes are highly conserved for chromosome compaction to ensure their faithful segregation in mitosis. Condensin II is present in the nucleus throughout the cell cycle, including interphase. The aim of these experiments is to investigate the changes of gene expression in knockdown of NCAPH2, a condensin II subunit, in mouse embryonic stem cells compared to their control cells. Overall design: Examination of gene expression of controls and NCAPH2 knockdown cells by RNA-seq

PubMed ID

28691095

Publication Title

Condensin II is anchored by TFIIIC and H3K4me3 in the mammalian genome and supports the expression of active dense gene clusters.

Total Samples

Submitter’s Institution

No associated institution

Authors

Yuen KC, Slaughter BD, Gerton JL

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE80041

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