A novel synthetic jumonji H3K27 demethylase inhibitor GSK-J4 exert immunosuppressive activities

SRP072847

Mus musculus

15 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Using RNA-seq, we report that jumonji H3K27 demethylase inhibitor, GSK-J4, exerts potent anti-inflammatory effects on LPS-stimulated BV-2 microglial cells. Overall design: Examination of effects of LPS-stimulated BV2 cells with or without GSKJ4 treatment, were generated by deep sequencing on an Illumina HiSeq 2000(101 cycles PE lane).

PubMed ID

27400875

Publication Title

Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia.

Total Samples

Submitter’s Institution

No associated institution

Authors

Das A, Kim SH, Arifuzzaman S, Yoon T, Chai JC, Lee YS, Park KS, Jung KH, Chai YG

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE79898

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