RNA-Sequencing of Klf6 silenced oligodendrocytes

We examine the role of Klf6 in oligodendrocyte progenitor cells and determine that Klf6 acts as a gp130-sensitive transactivator of the nuclear import factor importin-a5 (Impa5), a key controller of nuclear trafficking in oligodendrocytes. Overall design: Examination of expression profiles of 2 different cell stages exposed to siRNA vs. control

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Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR